New Prime Minister Theresa May has made Boris Johnson, the former London mayor who led the Brexit campaign, foreign secretary in her new government.
He replaces Philip Hammond, who becomes chancellor. Ex-Energy Secretary Amber Rudd is home secretary and Eurosceptic David Davis is the Brexit minister.
No 10 said ex-Chancellor George Osborne had resigned from the government.
On arriving at Downing Street, Mrs May vowed to lead a government that works for all not just the â€œprivileged fewâ€.
The UKâ€™s second female prime minister promised to give people who were â€œjust managingâ€ and â€œworking around the clockâ€ more control over their lives.Image copyrightPA
Michael Fallon continues as defence secretary, and Liam Fox, who resigned as defence secretary in 2011, has a new role as international trade minister.
Mrs May has spoken of the need to reunite the Conservative Party after the EU referendum, in which she backed a Remain vote.
Her new line-up includes big jobs for prominent Leave campaigners Mr Johnson â€“ who was initially tipped as the next prime minister after the Brexit vote â€“ Mr Fox, and Mr Davis, whose job title is â€œsecretary of state for exiting the European Unionâ€.
On Twitter, Mr Osborne, who was chancellor throughout Mr Cameronâ€™s tenure, said it had been a â€œprivilegeâ€, adding: â€œOthers will judge â€“ I hope Iâ€™ve left the economy in a better state than I found it.â€Image copyrightPAImage caption Image copyrightPAImage caption Image copyrightAPImage caption
After returning from Buckingham Palace, where she was formally appointed as prime minister by the Queen, Mrs May made a speech from outside 10 Downing Street.
Her husband Philip was standing behind her as she highlighted the â€œprecious bondâ€ between England, Scotland, Wales and Northern Ireland and between â€œevery one of usâ€.
â€œThat means fighting against the burning injustice that if youâ€™re born poor you will die on average nine years earlier than others,â€ she said.
For an â€œordinary working class familyâ€, she added, â€œLife is much harder than many people in Westminster realise.â€
â€œWhen it comes to opportunity, we wonâ€™t entrench the advantages of the fortunate few, we will do everything we can to help anybody, whatever your background, to go as far as your talents will take you,â€ Mrs May said.
She also paid tribute to her predecessor, David Cameron, saying he had been a â€œgreat, modern prime ministerâ€.